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During aging, there is a decrease in mitochondrial biogenesis-related proteins (SIRT1 and PGC-1α) and mitophagy-related proteins (PINK1 and PARKIN)

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Recent studies have also found that DNA methylated promoters of CDO1 , TAC1 , HOXA9 and SOX17 can be detected in the urine of patients with NSCLC (Liu et al., 2020